ACSL1 antibody (N-Term)

Catalog No. ABIN2777591

This anti-ACSL1 antibody is a Rabbit Polyclonal antibody detecting ACSL1 in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio), Pig and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for ACSL1 antibody (N-Term) (ABIN2777591)

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio), Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ACSL1 Antibody

Binding Specificity: N-Term

Sequence: ALLDSDEPLV YFYDDVTTLY EGFQRGIQVS NNGPCLGSRK PDQPYEWLSY

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against ACSL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACSL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 698 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACSL1 antibody (ABIN2777591)

Soupene, Kuypers: "Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains." in: BMC molecular biology, Vol. 7, pp. 21, (2006) (PubMed).

Target Details for ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Alternative Name: ACSL1

Background: ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Protein Interaction Partner: SUMO2, PARK2, ATP4A, UBC, NR3C2, ECT2, UBD,
Protein Size: 698

Molecular Weight: 78 kDa

Gene ID: 2180

NCBI Accession: NM_001995, NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha