ACAT2 antibody (Middle Region)

Catalog No. ABIN2777595

The Rabbit Polyclonal anti-ACAT2 antibody (ABIN2777595) specifically detects ACAT2 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit samples.

Quick Overview for ACAT2 antibody (Middle Region) (ABIN2777595)

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ACAT2 Antibody

Binding Specificity: Middle Region

Purpose: ACAT2 Antibody - middle region

Sequence: SREDQDKVAV LSQNRTENAQ KAGHFDKEIV PVLVSTRKGL IEVKTDEFPR

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ACAT2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACAT2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093775

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACAT2

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Alternative Name: ACAT2

Background:

Background Information: Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Gene Name: Acetyl-CoA acetyltransferase 2

Alternative Symbols: ACAT2, ACTL

Protein Name: Acetyl-CoA acetyltransferase, cytosolic

Molecular Weight: 41kDa

Gene ID: 39

NCBI Accession: NP_005882

UniProt: Q9BWD1