ME1 antibody (C-Term)

Catalog No. ABIN2777598

The Rabbit Polyclonal anti-ME1 antibody (ABIN2777598) specifically detects ME1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Rabbit, Horse, Sheep, Cow, Goat and Guinea Pig samples.

Quick Overview for ME1 antibody (C-Term) (ABIN2777598)

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Sheep, Cow, Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ME1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ME1 Antibody

Binding Specificity: C-Term

Sequence: KAECSAEQCY KITKGRAIFA SGSPFDPVTL PNGQTLYPGQ GNNSYVFPGV

Predicted Reactivity: Cow: 85%, Dog: 92%, Goat: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 77%, Rabbit: 100%, Rat: 100%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against ME1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human ME1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ME1

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Alternative Name: ME1

Background: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
Alias Symbols: MES, HUMNDME
Protein Size: 406

Molecular Weight: 44 kDa

Gene ID: 4199

NCBI Accession: NM_002395, NP_002386

UniProt: P48163

Pathways: Regulation of Lipid Metabolism by PPARalpha