PPP1R13L antibody (Middle Region)

Catalog No. ABIN2777612

This Rabbit Polyclonal antibody specifically detects PPP1R13L in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Pig.It has been mentioned in 1 publication

Quick Overview for PPP1R13L antibody (Middle Region) (ABIN2777612)

Target: PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R13L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PPP1R13L Antibody

Binding Specificity: Middle Region

Purpose: PPP1R13L Antibody - middle region

Sequence: AQSVPELEEV ARVLAEIPRP LKRRGSMEQA PAVALPPTHK KQYQQIISRL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP1R13L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP1R13L

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109381

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PPP1R13L antibody (ABIN2777612)

Tomoda, Takahashi, Hibi, Asamitsu, Ishida, Kondo, Fujii, Okamoto: "Molecular docking analysis of the protein-protein interaction between RelA-associated inhibitor and tumor suppressor protein p53 and its inhibitory effect on p53 action." in: Cancer science, Vol. 99, Issue 3, pp. 615-22, (2008) (PubMed).

Target Details for PPP1R13L

Target: PPP1R13L (Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L))

Alternative Name: PPP1R13L

Background:

Background Information: IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53), whereas ASPP1 and ASPP2 are activators of p53.IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53, MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Protein phosphatase 1, regulatory subunit 13 like

Alternative Symbols: RAI, RAI4, IASPP, NKIP1

Protein Name: RelA-associated inhibitor

Molecular Weight: 89kDa

Gene ID: 10848

NCBI Accession: NP_006654

UniProt: Q8WUF5