PRDM4 antibody (C-Term)

Catalog No. ABIN2777623

The Rabbit Polyclonal anti-PRDM4 antibody is suitable to detect PRDM4 in samples from Human, Mouse, Rat, Pig, Cow, Dog, Horse, Rabbit, Saccharomyces cerevisiae, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PRDM4 antibody (C-Term) (ABIN2777623)

Target: PRDM4 (PR Domain Containing 4 (PRDM4))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Horse, Rabbit, Saccharomyces cerevisiae, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRDM4 Antibody

Binding Specificity: C-Term

Purpose: PRDM4 Antibody - C-terminal region

Sequence: GPTSSSSAPE EEEEDDSEEE DLADSVGTED CRINSAVYSA DESLSAHK

Predicted Reactivity: Cow: 90%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 92%, Rat: 90%, Yeast: 90%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against PRDM4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32839-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRDM4

Target: PRDM4 (PR Domain Containing 4 (PRDM4))

Alternative Name: PRDM4

Background:

Background Information: PRDM4 is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of PRDM4 protein has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF).The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.

Gene Name: PR domain containing 4

Alternative Symbols: PFM1

Protein Name: PR domain zinc finger protein 4

Molecular Weight: 88kDa

Gene ID: 11108

NCBI Accession: NP_036538

UniProt: Q9UKN5

Pathways: Neurotrophin Signaling Pathway