Hairless antibody (N-Term)

Catalog No. ABIN2777658

The Rabbit Polyclonal anti-Hairless antibody is suitable to detect Hairless in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Sheep. It has been validated for WB.

Quick Overview for Hairless antibody (N-Term) (ABIN2777658)

Target: Hairless (HR)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hairless antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Hairless Antibody

Binding Specificity: N-Term

Purpose: HR Antibody - N-terminal region

Sequence: GLPPEHPCDW PLTPHPWVYS GGQPKVPSAF SLGSKGFYYK DPSIPRLAKE

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 100%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against HR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32908-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Hairless

Target: Hairless (HR)

Alternative Name: HR

Background:

Background Information: HR is a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.

Gene Name: Hairless homolog (mouse)

Alternative Symbols: AU, MUHH, ALUNC, HYPT4, MUHH1, HSA277165

Protein Name: Protein hairless

Molecular Weight: 127kDa

Gene ID: 55806

NCBI Accession: NP_005135

UniProt: O43593