KDM3A antibody (C-Term)

Catalog No. ABIN2777661

There is 1 publication for this product available. The Rabbit Polyclonal anti-KDM3A antibody is suitable to detect KDM3A in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for KDM3A antibody (C-Term) (ABIN2777661)

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KDM3A Antibody

Binding Specificity: C-Term

Purpose: JMJD1A Antibody - C-terminal region

Sequence: HNLYSCIKVA EDFVSPEHVK HCFWLTQEFR YLSQTHTNHE DKLQVKNVIY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against JMJD1A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD1A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104652

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-KDM3A antibody (ABIN2777661)

Zhou, Sun, Ellen, Chen, Costa: "Arsenite alters global histone H3 methylation." in: Carcinogenesis, Vol. 29, Issue 9, pp. 1831-6, (2008) (PubMed).

Target Details for KDM3A

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Alternative Name: JMJD1A

Background:

Background Information: JMJD1A is a zinc finger protein that contains a jumonji domain.

Gene Name: Lysine (K)-specific demethylase 3A

Alternative Symbols: TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A

Protein Name: Lysine-specific demethylase 3A

Molecular Weight: 147kDa

Gene ID: 55818

NCBI Accession: NP_060903

UniProt: Q53S72

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect