REXO4 antibody (C-Term)

Catalog No. ABIN2777669

The Rabbit Polyclonal anti-REXO4 antibody is suitable to detect REXO4 in samples from Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for REXO4 antibody (C-Term) (ABIN2777669)

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REXO4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-REXO4 Antibody

Binding Specificity: C-Term

Purpose: REXO4 Antibody - C-terminal region

Sequence: QYGKCVYDKY VKPTEPVTDY RTAVSGIRPE NLKQGEELEV VQKEVAEMLK

Predicted Reactivity: Cow: 77%, Dog: 100%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human REXO4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110448

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for REXO4

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Alternative Name: REXO4

Background:

Background Information: The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.

Gene Name: REX4, RNA exonuclease 4 homolog (S. cerevisiae)

Alternative Symbols: REX4, XPMC2, XPMC2H

Protein Name: RNA exonuclease 4

Molecular Weight: 47kDa

Gene ID: 57109

NCBI Accession: NP_065118

UniProt: Q9GZR2