PBXIP1 antibody (N-Term)

Catalog No. ABIN2777673

This Rabbit Polyclonal antibody specifically detects PBXIP1 in WB. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for PBXIP1 antibody (N-Term) (ABIN2777673)

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBXIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PBXIP1 Antibody

Binding Specificity: N-Term

Purpose: PBXIP1 Antibody - N-terminal region

Sequence: AGGEGAGGEL GISLNMCLLG ALVLLGLGVL LFSGGLSESE TGPMEEVERQ

Predicted Reactivity: Cow: 92%, Human: 100%, Mouse: 92%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PBXIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PBXIP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108828

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PBXIP1

Target: PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))

Alternative Name: PBXIP1

Background:

Background Information: PBXIP1 is the regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.

Gene Name: Pre-B-cell leukemia homeobox interacting protein 1

Alternative Symbols: HPIP

Protein Name: Pre-B-cell leukemia transcription factor-interacting protein 1

Molecular Weight: 81kDa

Gene ID: 57326

NCBI Accession: NP_065385

UniProt: Q96AQ6