SOX18 antibody (Middle Region)

Catalog No. ABIN2777726

This anti-SOX18 antibody is a Rabbit Polyclonal antibody detecting SOX18 in WB. Suitable for Human, Mouse, Rat, Cow, Guinea Pig and Dog.

Quick Overview for SOX18 antibody (Middle Region) (ABIN2777726)

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX18 Antibody

Binding Specificity: Middle Region

Sequence: GSARAFRELP PLGAEFDGLG LPTPERSPLD GLEPGEAAFF PPPAAPEDCA

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against SOX18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX18

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Alternative Name: SOX18

Background: SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Alias Symbols: HLTS
Protein Interaction Partner: GKAP1, MECP2, MEF2C, HMGB1,
Protein Size: 384

Molecular Weight: 41 kDa

Gene ID: 54345

NCBI Accession: NM_018419, NP_060889

UniProt: P35713