SOX18 antibody (Middle Region)

Catalog No. ABIN2777726

The Rabbit Polyclonal anti-SOX18 antibody (ABIN2777726) specifically detects SOX18 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig and Dog samples.

Quick Overview for SOX18 antibody (Middle Region) (ABIN2777726)

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX18 Antibody

Binding Specificity: Middle Region

Sequence: GSARAFRELP PLGAEFDGLG LPTPERSPLD GLEPGEAAFF PPPAAPEDCA

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against SOX18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX18

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Alternative Name: SOX18

Background: SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Alias Symbols: HLTS
Protein Interaction Partner: GKAP1, MECP2, MEF2C, HMGB1,
Protein Size: 384

Molecular Weight: 41 kDa

Gene ID: 54345

NCBI Accession: NM_018419, NP_060889

UniProt: P35713