POU3F1 antibody (N-Term)

Catalog No. ABIN2777729

There are 2+ publications for this product available. The Rabbit Polyclonal anti-POU3F1 antibody is suitable to detect POU3F1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for POU3F1 antibody (N-Term) (ABIN2777729)

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU3F1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-POU3F1 Antibody

Binding Specificity: N-Term

Purpose: POU3F1 Antibody - N-terminal region

Sequence: YLPRGPGGGA GGTGPLMHPD AAAAAAAAAE RLHAGAAYRE VQKLMHHEWL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against POU3F1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108748

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-POU3F1 antibody (ABIN2777729)

Hashimoto, Tatsumi, Takeda, Naka, Ogane, Kameda, Kawachi, Shimizu, Sakai, Kamoshida: "Expression of organic anion-transporting polypeptide 1A2 and organic cation transporter 6 as a predictor of pathologic response to neoadjuvant chemotherapy in triple negative breast cancer." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 101-11, (2014) (PubMed).

Sumiyama, Washio-Watanabe, Ono, Yoshida, Hayakawa, Ueda: "Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 9, Issue 2, pp. 180-1, (1998) (PubMed).

Target Details for POU3F1

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Alternative Name: POU3F1

Background:

Background Information: POU3F1 is a member of the POU domain family of proteins, and regulates events during neurogenesis and myelination.

Gene Name: POU class 3 homeobox 1

Alternative Symbols: OCT6, OTF6, SCIP

Protein Name: POU domain, class 3, transcription factor 1

Molecular Weight: 45kDa

Gene ID: 5453

NCBI Accession: NP_002690

UniProt: Q03052