HSP70 1A antibody (Middle Region)

Catalog No. ABIN2777745

This anti-HSP70 1A antibody is a Rabbit Polyclonal antibody detecting HSP70 1A in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Sheep, Guinea Pig, Rabbit, Goat and Horse. This Primary Antibody has been cited in 1 publication.

Quick Overview for HSP70 1A antibody (Middle Region) (ABIN2777745)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Sheep, Guinea Pig, Rabbit, Goat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSP70 1A Antibody

Binding Specificity: Middle Region

Sequence: SLFEGIDFYT SITRARFEEL CSDLFRSTLE PVEKALRDAK LDKAQIHDLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against HSPA1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPA1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HSP70 1A antibody (ABIN2777745)

Narjoz, Marisa, Imbeaud, Paris, Delacroix, Beaune, De Waziers: "Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells." in: Chemical research in toxicology, Vol. 22, Issue 5, pp. 779-87, (2009) (PubMed).

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSPA1A

Background: HSPA1A is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.
Alias Symbols: HSP72, HSPA1, HSP70I, HSPA1B, HSP70-1, HSP70-1A
Protein Interaction Partner: UBC, TP53, NEDD1, HAUS1, CEP76, CEP72, HAUS2, AIRE, CEP250, TUBGCP2, TUBGCP3, SAE1, CEP57, AURKB, TUBG1, AURKA, SUMO2, TUBGCP4, PPP2R1A, LGALS3BP, EMD, CDKN1A, CDC20, SUMO3, STAU1, MDM2, TRIM25, ASB10, ASB16, WWOX, EZH2, BMI1, SUZ12, TUBA4A, EIF6, ALDOC,
Protein Size: 476

Molecular Weight: 52 kDa

Gene ID: 3303

NCBI Accession: NM_005345

UniProt: P08107

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process