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MRPS15 antibody (N-Term)

MRPS15 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777848
  • Target See all MRPS15 Antibodies
    MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MRPS15 antibody is un-conjugated
    Application
    • 25
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    RGYVVRKPAQ SRLDDDPPPS TLLKDYQNVP GIEKVDDVVK RLLSLEMANK
    Predicted Reactivity
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 83%, Rabbit: 86%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against MRPS15. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human MRPS15
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 257 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Davies, Rackham, Shearwood, Hamilton, Narsai, Whelan, Filipovska: "Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation." in: FEBS letters, Vol. 583, Issue 12, pp. 1853-8, (2009) (PubMed).

  • Target
    MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
    Alternative Name
    MRPS15 (MRPS15 Products)
    Synonyms
    CG4207 antibody, DmMRPS15 antibody, Dmel\\CG4207 antibody, MRP-S15 antibody, mRpS15 antibody, zgc:92862 antibody, MPR-S15 antibody, RPMS15 antibody, S15mt antibody, 1500003E24Rik antibody, 2410002B11Rik antibody, Mprs15 antibody, CG4207 gene product from transcript CG4207-RA antibody, mitochondrial ribosomal protein S15 antibody, mitochondrial ribosomal protein S15 L homeolog antibody, bonsai antibody, mrps15 antibody, MRPS15 antibody, mrpS15 antibody, mrps15.L antibody, Mrps15 antibody
    Background
    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS15 is a 28S subunit protein that belongs to the ribosomal protein S15P family.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.
    Alias Symbols: DC37, FLJ11564, MPR-S15, RPMS15, S15mt
    Protein Interaction Partner: GRSF1, UBC, PARK2, ESR2, PTCD3, CAND1, COPS5, CUL3, SUMO2, ICT1,
    Protein Size: 257
    Molecular Weight
    30 kDa
    Gene ID
    64960
    NCBI Accession
    NM_031280, NP_112570
    UniProt
    P82914
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