SNAIL antibody (N-Term)

Catalog No. ABIN2777859

This Rabbit Polyclonal antibody specifically detects SNAIL in WB. It exhibits reactivity toward Human, Rat, Guinea Pig, Horse and Cow.

Quick Overview for SNAIL antibody (N-Term) (ABIN2777859)

Target: SNAIL (SNAI1)

Reactivity: Human, Rat, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAIL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNAIL Antibody

Binding Specificity: N-Term

Sequence: RKPSDPNRKP NYSELQDSNP EFTFQQPYDQ AHLLAAIPPP EILNPTASLP

Predicted Reactivity: Cow: 77%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SNAI1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SNAI1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: SNAI1

Background: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
Alias Symbols: SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
Protein Interaction Partner: MTUS2, KRT31, TRIM23, ACTN2, MID2, NOTCH2NL, KRTAP10-3, KRT40, FBXL5, EZH2, RNF2, RING1, LATS2, UBC, BTRC, TP53, MDM2, GSK3B, HDAC1, CHD4, KDM1A, HDAC3, HDAC2, RCOR1, FBXL14, NOTCH1, HIST1H3A, EGR1, AJUBA, Sin3a, HOXD4, SUZ12, CTDSP1, CTDSPL, CTDSP2, QRIC
Protein Size: 264

Molecular Weight: 29 kDa

Gene ID: 6615

NCBI Accession: NM_005985, NP_005976

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling