MRGBP antibody (N-Term)

Catalog No. ABIN2777882

The Rabbit Polyclonal anti-MRGBP antibody is suitable to detect MRGBP in samples from Human, Mouse, Guinea Pig and Rat. It has been validated for WB.

Quick Overview for MRGBP antibody (N-Term) (ABIN2777882)

Target: MRGBP (MRG-Binding Protein (MRGBP))

Reactivity: Human, Mouse, Guinea Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRGBP Antibody

Binding Specificity: N-Term

Purpose: C20ORF20 Antibody - N-terminal region

Sequence: MGEAEVGGGG AAGDKGPGEA ATSPAEETVV WSPEVEVCLF HAMLGHKPVG

Predicted Reactivity: Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against C20ORF20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C20ORF20

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8105794

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Alternative Name: C20ORF20

Background:

Background Information: C20orf20 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.

Gene Name: Chromosome 20 open reading frame 20

Alternative Symbols: Eaf7, URCC4, MRG15BP, C20orf20

Protein Name: MRG-binding protein

Molecular Weight: 22kDa

Gene ID: 55257

NCBI Accession: NP_060740

UniProt: Q9NV56