TULP1 antibody (Middle Region)

Catalog No. ABIN2777956

The Rabbit Polyclonal anti-TULP1 antibody has been validated for WB. It is suitable to detect TULP1 in samples from Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for TULP1 antibody (Middle Region) (ABIN2777956)

Target: TULP1 (Tubby Like Protein 1 (TULP1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TULP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TULP1 Antibody

Binding Specificity: Middle Region

Sequence: EEEEAATVIK KSNQKGKAKG KGKKKAKEER APSPPVEVDE PREFVLRPAP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 91%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against TULP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TULP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 542 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TULP1

Target: TULP1 (Tubby Like Protein 1 (TULP1))

Alternative Name: TULP1

Background: TULP1 is required for normal development of photoreceptor synapses. TULP1 is also required for normal photoreceptor function and for long-term survival of photoreceptor cells. TULP1 interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells. TULP1 binds lipids, especially phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, phosphatidylinositol-5-phosphate, phosphatidylinositol-3,4-bisphosphate, phosphatidylinositol-4,5-bisphosphate, phosphatidylinositol-3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro).This gene encodes a member of the tubby-like gene family (TULPs). Members of this family have been identified in plants, vertebrates, and invertebrates and encode proteins of unknown function. TULP proteins share a conserved C-terminal region of approximately 200 amino acid residues. Mutations in this gene may be associated with retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RP14, TUBL1, LCA15
Protein Size: 542

Molecular Weight: 60 kDa

Gene ID: 7287

NCBI Accession: NM_003322, NP_003313

UniProt: O00294

Pathways: RTK Signaling