PIK3R3 antibody (Middle Region)

Catalog No. ABIN309699

The Rabbit Polyclonal anti-PIK3R3 antibody (ABIN309699) specifically detects PIK3R3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for PIK3R3 antibody (Middle Region) (ABIN309699)

Target: PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIK3R3 Antibody

Binding Specificity: Middle Region

Sequence: EYTRTSQEIQ MKRTAIEAFN ETIKIFEEQC HTQEQHSKEY IERFRREGNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PIK3R3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PIK3R3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 461 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIK3R3

Target: PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))

Alternative Name: PIK3R3

Background: PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Alias Symbols: DKFZp686P05226, FLJ41892, p55-GAMMA, p55
Protein Interaction Partner: FSD2, L3MBTL3, TRIM54, IRS4, LYN, MBIP, KHDRBS1, GRB2, ERBB3, ERBB2, EGFR, PIK3R2, CRK, RING1, QARS, PSME1, ORM1, KARS, GC, FGB, DARS, AMBP, VBP1, FBN3, DSN1, KLC2, MICAL1, KIAA1377, LUC7L2, TRMT2A, ABCB6, SERF1A, DRAP1, IRS2, TEC, RB1, PDGFRB, PIK3CA, IN
Protein Size: 461

Molecular Weight: 54 kDa

Gene ID: 8503

NCBI Accession: NM_003629, NP_003620

UniProt: Q92569