Claudin 7 antibody (Middle Region)

Catalog No. ABIN2778038

The Rabbit Polyclonal anti-Claudin 7 antibody has been validated for WB. It is suitable to detect Claudin 7 in samples from Human, Rat, Mouse, Dog, Cow, Horse, Sheep, Pig, Rabbit and Saccharomyces cerevisiae.

Quick Overview for Claudin 7 antibody (Middle Region) (ABIN2778038)

Target: Claudin 7 (CLDN7)

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Sheep, Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 7 Antibody

Binding Specificity: Middle Region

Sequence: GPAIFIGWAG SALVILGGAL LSCSCPGNES KAGYRVPRSY PKSNSSKEYV

Predicted Reactivity: Cow: 79%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 86%, Rat: 93%, Sheep: 79%, Yeast: 77%

Characteristics: This is a rabbit polyclonal antibody against CLDN7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 211 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 7

Target: Claudin 7 (CLDN7)

Alternative Name: CLDN7

Background: Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells.Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells (Zheng et al., 2003 [PubMed 14502431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CEPTRL2, CPETRL2, Hs.84359, claudin-1, CLDN-7
Protein Interaction Partner: SYNE4, HGD, LNX1, UBC, TJP1, RHOXF2, EPCAM,
Protein Size: 211

Molecular Weight: 22 kDa

Gene ID: 1366

NCBI Accession: NM_001307, NP_001298

UniProt: O95471

Pathways: Hepatitis C