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CIR1 antibody (Middle Region)

The Rabbit Polyclonal anti-CIR1 antibody has been validated for WB. It is suitable to detect CIR1 in samples from Human, Cow, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.
Catalog No. ABIN2778094

Quick Overview for CIR1 antibody (Middle Region) (ABIN2778094)

Target

CIR1

Reactivity

  • 14
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Cow, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host

  • 13
  • 1
Rabbit

Clonality

  • 13
  • 1
Polyclonal

Conjugate

  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CIR1 antibody is un-conjugated

Application

  • 7
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequence

    GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR KLDRLEKKKK

    Predicted Reactivity

    Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

    Characteristics

    This is a rabbit polyclonal antibody against CIR1. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of Human CIR1
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    CIR1

    Background

    CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
    Alias Symbols: CIR
    Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
    Protein Size: 450

    Molecular Weight

    52 kDa

    Gene ID

    9541

    NCBI Accession

    NM_004882, NP_004873

    UniProt

    Q86X95
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