CIR1 antibody (Middle Region)
Quick Overview for CIR1 antibody (Middle Region) (ABIN2778094)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR KLDRLEKKKK
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Predicted Reactivity
- Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against CIR1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human CIR1
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CIR1
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Background
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CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Alias Symbols: CIR
Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
Protein Size: 450 -
Molecular Weight
- 52 kDa
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Gene ID
- 9541
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NCBI Accession
- NM_004882, NP_004873
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UniProt
- Q86X95
Target
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