CIR1 antibody (Middle Region)

Catalog No. ABIN2778094

The Rabbit Polyclonal anti-CIR1 antibody is suitable to detect CIR1 in samples from Human, Cow, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio) and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for CIR1 antibody (Middle Region) (ABIN2778094)

Target: CIR1

Reactivity: Human, Cow, Horse, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CIR1 Antibody

Binding Specificity: Middle Region

Purpose: CIR1 Antibody - middle region

Sequence: GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR KLDRLEKKKK

Predicted Reactivity: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CIR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CIR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33736-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CIR1

Target: CIR1

Background:

Background Information: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.

Gene Name: corepressor interacting with RBPJ, 1

Alternative Symbols: CIR

Protein Name: Corepressor interacting with RBPJ 1

Molecular Weight: 52kDa

Gene ID: 9541

NCBI Accession: NP_004873

UniProt: Q86X95