HAND1 antibody (N-Term)

Catalog No. ABIN2778103

The Rabbit Polyclonal anti-HAND1 antibody (ABIN2778103) specifically detects HAND1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Sheep, Guinea Pig, Dog and Horse samples.

Quick Overview for HAND1 antibody (N-Term) (ABIN2778103)

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Guinea Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAND1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HAND1 Antibody

Binding Specificity: N-Term

Purpose: HAND1 Antibody - N-terminal region

Sequence: CHQERPYFQS WLLSPADAAP DFPAGGPPPA AAAAATAYGP DARPGQSPGR

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against HAND1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAND1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33748-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Alternative Name: HAND1

Background:

Background Information: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Gene Name: Heart and neural crest derivatives expressed 1

Alternative Symbols: Hxt, eHand, Thing1, bHLHa27

Protein Name: Heart- and neural crest derivatives-expressed protein 1

Molecular Weight: 23

Gene ID: 9421

NCBI Accession: NP_004812

UniProt: O96004

Pathways: Tube Formation