Asialoglycoprotein Receptor 1 antibody (Middle Region)

Catalog No. ABIN2778132

The Rabbit Polyclonal anti-Asialoglycoprotein Receptor 1 antibody is suitable to detect Asialoglycoprotein Receptor 1 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for Asialoglycoprotein Receptor 1 antibody (Middle Region) (ABIN2778132)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Asialoglycoprotein Receptor 1 Antibody

Binding Specificity: Middle Region

Purpose: ASGR1 Antibody - middle region

Sequence: RKMKSLESQL EKQQKDLSED HSSLLLHVKQ FVSDLRSLSC QMAALQGNGS

Predicted Reactivity: Cow: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rat: 92%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against ASGR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middlel region of human ASGR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33805-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1

Background:

Background Information: ASGR1 encodes for a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.

Gene Name: Asialoglycoprotein receptor 1

Alternative Symbols: HL-1, ASGPR, ASGPR1, CLEC4H1

Protein Name: ASGR1 protein EMBL CAG46849.1

Molecular Weight: 33 kDa

Gene ID: 432

NCBI Accession: NP_001662

UniProt: P07306

Pathways: Thyroid Hormone Synthesis