C4BPB antibody (N-Term)

Catalog No. ABIN2778139

There is 1 publication for this product available. The Rabbit Polyclonal anti-C4BPB antibody is suitable to detect C4BPB in samples from Human, Dog and Pig. It has been validated for WB and IHC.

Quick Overview for C4BPB antibody (N-Term) (ABIN2778139)

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Reactivity: Human, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4BPB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-C4BPB Antibody

Binding Specificity: N-Term

Purpose: C4BPB Antibody - N-terminal region

Sequence: CCLMVAWRVS ASDAEHCPEL PPVDNSIFVA KEVEGQILGT YVCIKGYHLV

Predicted Reactivity: Dog: 86%, Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against C4BPB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C4BPB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33814-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-C4BPB antibody (ABIN2778139)

Emery, Erdman, Bowen, Newton, Winchell, Meyer, Tong, Cook, Holloway, McCaustland, Rota, Bankamp, Lowe, Ksiazek, Bellini, Anderson: "Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus." in: Emerging infectious diseases, Vol. 10, Issue 2, pp. 311-6, (2004) (PubMed).

Target Details for C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Alternative Name: C4BPB

Background:

Background Information: C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.

Gene Name: Complement component 4 binding protein, beta

Alternative Symbols: C4BP

Protein Name: C4b-binding protein beta chain

Molecular Weight: 28kDa

Gene ID: 725

NCBI Accession: NP_000707

UniProt: P20851

Pathways: Complement System