Fetuin A antibody (N-Term)

Catalog No. ABIN2778140

Product Details anti-Fetuin A Antibody

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Binding Specificity: N-Term

Reactivity: Human, Rat, Guinea Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fetuin A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AQLWGCHSAP HGPGLIYRQP NCDDPETEEA ALVAIDYINQ NLPWGYKHTL

Predicted Reactivity: Dog: 86%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AHSG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AHSG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 367 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Fetuin A antibody (ABIN2778140)

Edvardsson Rasmussen, Lundström, Eriksson, Rask-Andersen, Liu, Laurell: "The Acute Effects of Furosemide on Na-K-Cl Cotransporter-1, Fetuin-A and Pigment Epithelium-Derived Factor in the Guinea Pig Cochlea." in: Frontiers in molecular neuroscience, Vol. 15, pp. 842132, (2022) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Gil-Dones, Darde, Alonso-Orgaz, Lopez-Almodovar, Mourino-Alvarez, Padial, Vivanco, Barderas: "Inside human aortic stenosis: a proteomic analysis of plasma." in: Journal of proteomics, Vol. 75, Issue 5, pp. 1639-53, (2012) (PubMed).

Target Details for Fetuin A

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Alternative Name: AHSG (AHSG Products)

Background: Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: A2HS, AHS, FETUA, HSGA
Protein Interaction Partner: SUMO1, UBC, NEDD8, ATF2, ALB, VKORC1, PPP5C, FBXO2, PSMA3, GRB2, CDC42, Mad2l1, Smad3, Hsd17b7, RRAS2, INSR, DCN,
Protein Size: 367

Molecular Weight: 39 kDa

Gene ID: 197

NCBI Accession: NM_001622, NP_001613

UniProt: P02765