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TRP63 antibody (Middle Region)

TRP63 Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778222
  • Target See all TRP63 Antibodies
    TRP63 (Transformation Related Protein 63 (TRP63))
    Binding Specificity
    Middle Region
    Reactivity
    Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This TRP63 antibody is un-conjugated
    Application
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VTLETRDGQV LGRRCFEARI CACPGRDRKA DEDSIRKQQV SDSAKNGDGT
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against Trp63. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product TRP63 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 461 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRP63 (Transformation Related Protein 63 (TRP63))
    Alternative Name
    Trp63 (TRP63 Products)
    Synonyms
    AI462811 antibody, Ket antibody, P51/P63 antibody, P63 antibody, P73l antibody, Tp63 antibody, Trp53rp1 antibody, transformation related protein 63 antibody, Trp63 antibody
    Background
    This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.
    Alias Symbols: AI462811, Ket, MGC115972, P51/P63, P63, P73l, Tp63, Trp53rp1
    Protein Interaction Partner: Trp53, Dlx6, Dlx5, Abbp1, Trp73, Perp,
    Protein Size: 461
    Molecular Weight
    50 kDa
    Gene ID
    22061
    NCBI Accession
    NM_001114978, NP_001108450
    UniProt
    Q9H3D4
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