CCRL2 antibody (N-Term)

Catalog No. ABIN2778230

This Rabbit Polyclonal antibody specifically detects CCRL2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for CCRL2 antibody (N-Term) (ABIN2778230)

Target: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCRL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCRL2 Antibody

Binding Specificity: N-Term

Purpose: CCRL2 Antibody - N-terminal region

Sequence: LSAQLVPSLC SAVFVIGVLD NLLVVLILVK YKGLKRVENI YLLNLAVSNL

Predicted Reactivity: Cow: 77%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 90%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against CCRL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCRL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCRL2

Target: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Alternative Name: CCRL2

Background:

Background Information: CCRL2 is a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. CCRL2 gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.

Gene Name: Chemokine (C-C motif) receptor-like 2

Alternative Symbols: HCR, CKRX, CRAM, ACKR5, CRAM-A, CRAM-B

Protein Name: C-C chemokine receptor-like 2

Molecular Weight: 39kDa

Gene ID: 9034

NCBI Accession: NP_003956

UniProt: O00421