REG1B antibody (N-Term)

Catalog No. ABIN2778231

The Rabbit Polyclonal anti-REG1B antibody is suitable to detect REG1B in samples from Human. It has been validated for WB.

Quick Overview for REG1B antibody (N-Term) (ABIN2778231)

Target: REG1B (Regenerating Islet-Derived 1 beta (REG1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REG1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-REG1B Antibody

Binding Specificity: N-Term

Purpose: REG1B Antibody - N-terminal region

Sequence: MAQTNSFFML ISSLMFLSLS QGQESQTELP NPRISCPEGT NAYRSYCYYF

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against REG1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human REG1B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34029-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for REG1B

Target: REG1B (Regenerating Islet-Derived 1 beta (REG1B))

Alternative Name: REG1B

Background:

Background Information: REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. REG1B may be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Regenerating islet-derived 1 beta

Alternative Symbols: REGH, REGL, PSPS2, REGI-BETA

Protein Name: Lithostathine-1-beta

Molecular Weight: 16kDa

Gene ID: 5968

NCBI Accession: NP_006498

UniProt: P48304