RGS14 antibody (Middle Region)

Catalog No. ABIN2778237

This Rabbit Polyclonal antibody specifically detects RGS14 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Rabbit and Dog.

Quick Overview for RGS14 antibody (Middle Region) (ABIN2778237)

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS14 Antibody

Binding Specificity: Middle Region

Sequence: LGSPDTARKK PKLKPGKSLP LGVEELGQLP LAEGPCGRPL RKSFRREMTG

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Rgs14. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Rgs14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 547 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Alternative Name: Rgs14

Background: Rgs14 acts as a regulator of G protein signaling (RGS). It modulates G protein alpha subunits nucleotide exchange and hydrolysis activities by functioning either as a GTPase-activating protein (GAP), thereby driving G protein alpha subunits into their inactive GDP-bound form, or as a GDP-dissociation inhibitor (GDI).
Alias Symbols: -
Protein Interaction Partner: Rufy3,
Protein Size: 547

Molecular Weight: 60 kDa

Gene ID: 51791

NCBI Accession: NM_016758, NP_058038

UniProt: P97492

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling