RGS13 antibody (Middle Region)

Catalog No. ABIN2778239

This Rabbit Polyclonal antibody specifically detects RGS13 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse and Rabbit.

Quick Overview for RGS13 antibody (Middle Region) (ABIN2778239)

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS13 Antibody

Binding Specificity: Middle Region

Sequence: WSRISRAKKL YKIYIQPQSP REINIDSSTR ETIIRNIQEP TETCFEEAQK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RGS13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 159 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS13

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Alternative Name: RGS13

Background: The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.
Protein Interaction Partner: GNAI2, GNA11, UBC, PRKACA, CREB1, GNAQ,
Protein Size: 159

Molecular Weight: 17 kDa

Gene ID: 6003

NCBI Accession: NM_144766, NP_658912

UniProt: O14921

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling