PPARA antibody (C-Term)

Catalog No. ABIN2778248

The Rabbit Polyclonal anti-PPARA antibody has been validated for WB and IHC. It is suitable to detect PPARA in samples from Human, Mouse, Rat, Dog, Horse, Cow, Pig, Goat, Guinea Pig, Rabbit, Sheep and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for PPARA antibody (C-Term) (ABIN2778248)

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig, Goat, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPARA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PPARA Antibody

Binding Specificity: C-Term

Sequence: LHLQSNHPDD TFLFPKLLQK MVDLRQLVTE HAQLVQVIKK TESDAALHPL

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Ppara. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 468 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PPARA antibody (ABIN2778248)

Gu, Yang, Lin, Li, Li, Zhong, Peng, Cui: "Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting." in: Hepatology (Baltimore, Md.), Vol. 60, Issue 6, pp. 1929-41, (2014) (PubMed).

Target Details for PPARA

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Alternative Name: Ppara

Background: As a nuclear steroid receptor, Ppara heterodimerizes with retinoid-X receptor (RXR), and binds to peroxisome proliferator response elements (PPREs) to initiate the transcriptional regulation of target genes.
Alias Symbols: PPAR
Protein Interaction Partner: HSP90AA1, Mdm2, Ubc, NRIP1, Dut,
Protein Size: 468

Molecular Weight: 51 kDa

Gene ID: 25747

NCBI Accession: NM_013196, NP_037328

UniProt: P37230

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C