BRD8 antibody (Middle Region)

Catalog No. ABIN2778259

The Rabbit Polyclonal anti-BRD8 antibody is suitable to detect BRD8 in samples from Human, Rabbit, Dog, Horse and Cow. It has been validated for WB.

Quick Overview for BRD8 antibody (Middle Region) (ABIN2778259)

Target: BRD8 (Bromodomain Containing 8 (BRD8))

Reactivity: Human, Rabbit, Dog, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRD8 Antibody

Binding Specificity: Middle Region

Purpose: BRD8 Antibody - middle region

Sequence: LRSQDLDEEL GSTAAGEIVE ADVAIGKGDE TPLTNVKTEA SPESMLSPSH

Predicted Reactivity: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Rabbit: 85%

Characteristics: This is a rabbit polyclonal antibody against BRD8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRD8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34090-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRD8

Target: BRD8 (Bromodomain Containing 8 (BRD8))

Alternative Name: BRD8

Background:

Background Information: BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator.The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.

Gene Name: Bromodomain containing 8

Alternative Symbols: SMAP, p120, SMAP2

Protein Name: Bromodomain-containing protein 8

Molecular Weight: 135kDa

Gene ID: 10902

NCBI Accession: NP_631938

UniProt: Q9H0E9