PREB antibody (N-Term)

Catalog No. ABIN2778276

This Rabbit Polyclonal antibody specifically detects PREB in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Guinea Pig.It has been mentioned in 1 publication

Quick Overview for PREB antibody (N-Term) (ABIN2778276)

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PREB Antibody

Binding Specificity: N-Term

Purpose: PREB Antibody - N-terminal region

Sequence: RVENLQAVQT DFSSDPLQKV VCFNHDNTLL ATGGTDGYVR VWKVPSLEKV

Predicted Reactivity: Cow: 83%, Dog: 92%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PREB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PREB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34130-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PREB antibody (ABIN2778276)

Edgar: "The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12." in: BMC genomics, Vol. 4, Issue 1, pp. 18, (2003) (PubMed).

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: PREB

Background:

Background Information: PREB encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p.

Gene Name: Prolactin regulatory element binding

Alternative Symbols: SEC12

Protein Name: Prolactin regulatory element-binding protein

Molecular Weight: 45kDa

Gene ID: 10113

NCBI Accession: NP_037520

UniProt: Q9HCU5

Pathways: ER-Nucleus Signaling