TRIM13 antibody (Middle Region)

Catalog No. ABIN2778287

The Rabbit Polyclonal anti-TRIM13 antibody (ABIN2778287) specifically detects TRIM13 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for TRIM13 antibody (Middle Region) (ABIN2778287)

Target: TRIM13 (Tripartite Motif Containing 13 (TRIM13))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM13 Antibody

Binding Specificity: Middle Region

Sequence: KVKEFFEKLQ HTLDQKKNEI LSDFETMKLA VMQAYDPEIN KLNTILQEQR

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RFP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RFP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 407 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM13

Target: TRIM13 (Tripartite Motif Containing 13 (TRIM13))

Alternative Name: RFP2

Background: The protein encoded by RFP2 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies near the nucleus, but its function is unknown. RFP2 is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia.
Alias Symbols: CAR, LEU5, RFP2, DLEU5, RNF77
Protein Interaction Partner: GMCL1, IKBKG, TRIM13, VCP, UBC, DDOST, CALM1, ATP2A2, UBE2D2, ZFYVE1, SQSTM1, ROBO2, CACNA1C, ARHGDIA, MDM2, AKT1,
Protein Size: 407

Molecular Weight: 45 kDa

Gene ID: 10206

NCBI Accession: NM_052811, NP_434698

UniProt: O60858