CSRP3 antibody (Cysteine and Glycine-Rich Protein 3) (Middle Region)

Details for Product anti-CSRP3 Antibody No. ABIN2778310, Supplier: Log in to see
Antigen
  • CLP
  • CMD1M
  • CMH12
  • CRP3
  • LMO4
  • MLP
  • MMLP
  • csrp3
  • zgc:103468
  • CSRP3
  • csrp3-a
  • cysteine and glycine rich protein 3
  • cysteine and glycine-rich protein 3
  • cysteine and glycine-rich protein 3 (cardiac LIM protein)
  • cysteine and glycine rich protein 3 L homeolog
  • CSRP3
  • Csrp3
  • csrp3
  • csrp3.L
Epitope
Middle Region
12
11
10
7
5
3
2
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
80
31
23
11
7
6
5
4
3
3
2
1
1
Host
Rabbit
53
18
7
2
Clonality
Polyclonal
Conjugate
This CSRP3 antibody is un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
76
49
22
13
6
3
3
2
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CSRP3
Blocking Peptide Blocking peptide for this product available: ABIN975383
Sequence QGAGCLSTDT GEHLGLQFQQ SPKPARSVTT SNPSKFTAKF GESEKCPRCG
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against CSRP3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others CSRP3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CSRP3 (CSRP3 Antibody Abstract)
Background The CSRP3 gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in CSRP3 are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans.
Alias Symbols: CLP, MLP, CRP3, LMO4, CMD1M, CMH12
Protein Interaction Partner: UBC, HDAC4, LDHD, SPTB, NHLH1, MYF6, MYOG, MYOD1, ACTN1,
Protein Size: 194
Molecular Weight 21 kDa
Gene ID 8048
NCBI Accession NM_003476, NP_003467
UniProt P50461
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 194 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Cysteine and Glycine-Rich Protein 3 (CSRP3) (Middle Region) antibody (ABIN2778310) WB Suggested Anti-CSRP3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posi...
Western Blotting (WB) image for anti-Cysteine and Glycine-Rich Protein 3 (CSRP3) (Middle Region) antibody (ABIN2778310) Host: Rabbit Target Name: CSRP3 Sample Tissue: Human HCT116 Whole Cell Antibody...
Product cited in: Roberts, Childs, Brown, Davis, Booth: "Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 112, Issue 8, pp. 1291-9, 2012 (PubMed).

Background publications Geier, Perrot, Ozcelik, Binner, Counsell, Hoffmann, Pilz, Martiniak, Gehmlich, van der Ven, Fürst, Vornwald, von Hodenberg, Nürnberg, Scheffold, Dietz, Osterziel: "Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy." in: Circulation, Vol. 107, Issue 10, pp. 1390-5, 2003 (PubMed).

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