CSRP3 antibody (Middle Region)

Catalog No. ABIN2778310

Cited in 1 publication. The Rabbit Polyclonal anti-CSRP3 antibody (ABIN2778310) specifically detects CSRP3 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit, Horse and Guinea Pig samples.

Quick Overview for CSRP3 antibody (Middle Region) (ABIN2778310)

Target: CSRP3 (Cysteine and Glycine-Rich Protein 3 (CSRP3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSRP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSRP3 Antibody

Binding Specificity: Middle Region

Purpose: CSRP3 Antibody - middle region

Sequence: QGAGCLSTDT GEHLGLQFQQ SPKPARSVTT SNPSKFTAKF GESEKCPRCG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CSRP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CSRP3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34181-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CSRP3 antibody (ABIN2778310)

Roberts, Childs, Brown, Davis, Booth: "Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 112, Issue 8, pp. 1291-9, (2012) (PubMed).

Target Details for CSRP3

Target: CSRP3 (Cysteine and Glycine-Rich Protein 3 (CSRP3))

Alternative Name: CSRP3

Background:

Background Information: The CSRP3 gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in CSRP3 are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans.

Gene Name: Cysteine and glycine-rich protein 3 (cardiac LIM protein)

Alternative Symbols: CLP, MLP, CRP3, LMO4, CMD1M, CMH12

Protein Name: Cysteine and glycine-rich protein 3

Molecular Weight: 21kDa

Gene ID: 8048

NCBI Accession: NP_003467

UniProt: P50461