BMI1 antibody (C-Term)

Catalog No. ABIN2778334

The Rabbit Polyclonal anti-BMI1 antibody has been validated for WB. It is suitable to detect BMI1 in samples from Human, Mouse, Rat, Rabbit, Dog, Cow, Horse, Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for BMI1 antibody (C-Term) (ABIN2778334)

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Horse, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMI1 Antibody

Binding Specificity: C-Term

Sequence: TPVQSPHPQF PHISSTMNGT SNSPSGNHQS SFANRPRKSS VNGSSATSSG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against PCGF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PCGF4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMI1

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Alternative Name: PCGF4

Background: PCGF4 regulates telomerase expression in MECs and plays a role in the development of human breast cancer.
Alias Symbols: PCGF4, RNF51, FLVI2/BMI1
Protein Interaction Partner: RNF2, RING1, NDEL1, PHC2, UBC, TP53, HIST4H4, LENG8, PAXBP1, SFXN1, TIMM50, ZC3HAV1L, NME1, NHP2L1, NFX1, NDUFA4, NCL, NCBP1, MAGOH, CAPRIN1, KTN1, ILF3, ILF2, IK, HSPA1A, HIST1H2BB, HIST1H2BD, GTF3C1, GATA2, FUS, EWSR1, FBL, ERH, EP300, ELAVL1, ELAVL2, D
Protein Size: 326

Molecular Weight: 37 kDa

Gene ID: 648

NCBI Accession: NM_005180, NP_005171

UniProt: P35226

Pathways: Cell Division Cycle, Autophagy