KDM2B antibody (Middle Region)

Catalog No. ABIN2778398

This Rabbit Polyclonal antibody specifically detects KDM2B in WB. It exhibits reactivity toward Human, Mouse, Dog, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for KDM2B antibody (Middle Region) (ABIN2778398)

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM2B Antibody

Binding Specificity: Middle Region

Purpose: FBXL10 Antibody - middle region

Sequence: LSFFKRCGNI CHIDLRYCKQ VTKEGCEQFI AEMSVSVQFG QVEEKLLQKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FBXL10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXL10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39706-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Alternative Name: FBXL10

Background:

Background Information: FBXL10 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which fun

Gene Name: Lysine (K)-specific demethylase 2B

Alternative Symbols: CXXC2, Fbl10, PCCX2, FBXL10, JHDM1B

Protein Name: Lysine-specific demethylase 2B

Molecular Weight: 152kDa

Gene ID: 84678

NCBI Accession: NP_115979

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effect