TRIM5 antibody (N-Term)

Catalog No. ABIN2778419

The Rabbit Polyclonal anti-TRIM5 antibody has been validated for WB. It is suitable to detect TRIM5 in samples from Human.

Quick Overview for TRIM5 antibody (N-Term) (ABIN2778419)

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM5 Antibody

Binding Specificity: N-Term

Sequence: CQACLTANHK KSMLDKGESS CPVCRISYQP ENIRPNRHVA NLVEKLREVK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM5

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Alternative Name: TRIM5

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-co
Alias Symbols: RNF88, TRIM5alpha
Protein Interaction Partner: UBC, PRKCG, gag, OTUD6A, OTUB2, USP21, USP39, USP15, USP2, USP5, TNFAIP3, UBE2D2, MAP3K7, MAP3K1, TAB3, TAB2, IKBKG, MKRN3, TRIM21, MNAT1, TRIM6, TRIM5, TRIM34, TRIM35, TRIM32, SQSTM1, UBB, PSMD7, PSMC5, PSMC4, PSMC2, MAP3K11, SUMO1, ZWINT, LZTR1, PCBD1,
Protein Size: 493

Molecular Weight: 56 kDa

Gene ID: 85363

NCBI Accession: NM_033034, NP_149023

UniProt: Q9C035

Pathways: Activation of Innate immune Response