MSL3 antibody (N-Term)

Catalog No. ABIN2778441

This Rabbit Polyclonal antibody specifically detects MSL3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow and Guinea Pig.

Quick Overview for MSL3 antibody (N-Term) (ABIN2778441)

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MSL3 Antibody

Binding Specificity: N-Term

Sequence: MSASEGMKFK FHSGEKVLCF EPDPTKARVL YDAKIVDVIV GKDEKGRKIP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MSL3L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MSL3L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 521 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MSL3

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Alternative Name: MSL3L1

Background: MSL3L1 is a nuclear protein, which is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms.
Alias Symbols: DKFZP586J1822, MSL3L1
Protein Interaction Partner: PAF1, DYRK1B, SOX2, UBC, CDK6, APP, HIST4H4, HIST3H3, MSL1, KAT8, PRKDC, MSL2, HIST1H4A, HIST1H3A,
Protein Size: 521

Molecular Weight: 60 kDa

Gene ID: 10943

NCBI Accession: NM_078629, NP_523353

UniProt: Q8N5Y2