DACH1 antibody (C-Term)

Catalog No. ABIN2778444

This Rabbit Polyclonal antibody specifically detects DACH1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Rabbit, Guinea Pig, Dog and Zebrafish (Danio rerio).

Quick Overview for DACH1 antibody (C-Term) (ABIN2778444)

Target: DACH1 (Dachshund 1 (DACH1))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Guinea Pig, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DACH1 Antibody

Binding Specificity: C-Term

Purpose: DACH1 Antibody - C-terminal region

Sequence: TLKQAASTDS LRVLNDSLTP EIEADRSGGR TDAERTIQDG RLYLKTTVMY

Predicted Reactivity: Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DACH1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DACH1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39788-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DACH1

Target: DACH1 (Dachshund 1 (DACH1))

Alternative Name: DACH1

Background:

Background Information: This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Dachshund homolog 1 (Drosophila)

Alternative Symbols: DACH

Protein Name: Dachshund homolog 1

Molecular Weight: 57kDa

Gene ID: 1602

NCBI Accession: NP_542938

UniProt: Q9UI36

Pathways: Feeding Behaviour