HOXA9 antibody (Middle Region)

Catalog No. ABIN2778526

There is 1 publication for this product available. The Rabbit Polyclonal anti-HOXA9 antibody is suitable to detect HOXA9 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio) and Sheep. It has been validated for WB.

Quick Overview for HOXA9 antibody (Middle Region) (ABIN2778526)

Target: HOXA9 (Homeobox A9 (HOXA9))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXA9 Antibody

Binding Specificity: Middle Region

Purpose: HOXA9 Antibody - middle region

Sequence: KEFLFNMYLT RDRRYEVARL LNLTERQVKI WFQNRRMKMK KINKDRAKDE

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HOXA9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39932-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXA9 antibody (ABIN2778526)

Wang, Zeng, Chen, Ding, Zhong, Zhao, Wang, Sarver, Koller, Zhi, Ma, Yu, Chen, Huang: "BRCA1 is a negative modulator of the PRC2 complex." in: The EMBO journal, Vol. 32, Issue 11, pp. 1584-97, (2013) (PubMed).

Target Details for HOXA9

Target: HOXA9 (Homeobox A9 (HOXA9))

Alternative Name: HOXA9

Background:

Background Information: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and the protein is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Homeobox A9

Alternative Symbols: HOX1, ABD-B, HOX1G, HOX1.7

Protein Name: Homeobox protein Hox-A9

Molecular Weight: 30kDa

Gene ID: 3205

NCBI Accession: NP_689952

UniProt: P31269