RPL6 antibody (N-Term)

Catalog No. ABIN2778674

This anti-RPL6 antibody is a Rabbit Polyclonal antibody detecting RPL6 in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Horse and Cow.

Quick Overview for RPL6 antibody (N-Term) (ABIN2778674)

Target: RPL6 (Ribosomal Protein L6 (RPL6))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPL6 Antibody

Binding Specificity: N-Term

Sequence: AGEKVEKPDT KEKKPEAKKV DAGGKVKKGN LKAKKPKKGK PHCSRNPVLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 87%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against RPL6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPL6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 288 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPL6

Target: RPL6 (Ribosomal Protein L6 (RPL6))

Alternative Name: RPL6

Background: RPL6 is a ribosomal protein that is a component of the 60S subunit. RPL6 belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: L6, TXREB1, SHUJUN-2, TAXREB107
Protein Interaction Partner: HUWE1, UBC, ELF3, CEP250, TUBG1, TP53, SUMO3, STAU1, SUMO1, MDM2, WWOX, RPA3, RPA2, RPA1, RNF2, rev, PARK2, FBXO6, TARDBP, IGSF8, ICAM1, CD81, PAN2, IL7R, FN1, CSNK2A1, SEL1L, IVNS1ABP, UBL4A, NPAS2, ND1, EIF4A3, YWHAE, VCP, MAGOH, ESR1, NOLC1, DDX21, RPL
Protein Size: 288

Molecular Weight: 32 kDa

Gene ID: 6128

NCBI Accession: NM_001024662, NP_001019833

UniProt: Q02878