CCBL2 antibody (N-Term)

Catalog No. ABIN2778707

There is 1 publication for this product available. The Rabbit Polyclonal anti-CCBL2 antibody is suitable to detect CCBL2 in samples from Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for CCBL2 antibody (N-Term) (ABIN2778707)

Target: CCBL2 (Cysteine Conjugate-beta Lyase 2 (CCBL2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCBL2 Antibody

Binding Specificity: N-Term

Purpose: KYAT3 Antibody - N-terminal region

Sequence: SGRAKFLKTI SSSKILGFST SAKMSLKFTN AKRIEGLDSN VWIEFTKLAA

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 91%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against RP11-82K18.3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RP11-82K18.3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098247

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CCBL2 antibody (ABIN2778707)

Marques, Dupanloup, Vinckenbosch, Reymond, Kaessmann: "Emergence of young human genes after a burst of retroposition in primates." in: PLoS biology, Vol. 3, Issue 11, pp. e357, (2005) (PubMed).

Target Details for CCBL2

Target: CCBL2 (Cysteine Conjugate-beta Lyase 2 (CCBL2))

Alternative Name: KYAT3

Background:

Background Information: This gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid, which is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping.

Gene Name: kynurenine aminotransferase 3

Alternative Symbols: KAT3, CCBL2, KATIII

Protein Name: kynurenine--oxoglutarate transaminase 3

Molecular Weight: 46kDa

Gene ID: 56267

NCBI Accession: NP_001008662

UniProt: Q6YP21