SIP1 antibody (Middle Region)

Catalog No. ABIN2778712

The Rabbit Polyclonal anti-SIP1 antibody has been validated for WB. It is suitable to detect SIP1 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Pig.

Quick Overview for SIP1 antibody (Middle Region) (ABIN2778712)

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIP1 Antibody

Binding Specificity: Middle Region

Sequence: HSLIRQLARR CSEVRLLVDS KDDERVPALN LLICLVSRYF DQRDLADEPS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 265 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIP1

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Alternative Name: SIP1

Background: Part of the core SMN complex which plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
Alias Symbols: GEMIN2, SIP1-delta, SIP1
Protein Interaction Partner: BMI1, RN7SL1, HDAC11, MMS19, vpr, IQCB1, GEMIN6, GEMIN7, GEMIN8, GEMIN4, RNU1-1, GEMIN5, DDX20, STRAP, SRP54, SRP9, SMN1, RNU2-1, COPA, ELAVL1, SNRPN, RAD50, IKBKG, STXBP3, SRSF4, SMN2, SRSF3, DHX9, GEMIN2, STXBP2, SNRPD1, SNRPD3, SNRPD2, SRSF2, SRSF1, U2
Protein Size: 265

Molecular Weight: 30 kDa

Gene ID: 8487

NCBI Accession: NM_001009182, NP_001009182

Pathways: Ribonucleoprotein Complex Subunit Organization, Tube Formation