FXR1 antibody (C-Term)

Catalog No. ABIN2778725

The Rabbit Polyclonal anti-FXR1 antibody is suitable to detect FXR1 in samples from Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig and Cow. It has been validated for WB.

Quick Overview for FXR1 antibody (C-Term) (ABIN2778725)

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FXR1 Antibody

Binding Specificity: C-Term

Purpose: FXR1 Antibody - C-terminal region

Sequence: EQLRQIGSRS YSGRGRGRRG PNYTSGYGTN SELSNPSETE SERKDELSDW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FXR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FXR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100977

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FXR1

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Alternative Name: FXR1

Background:

Background Information: FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit.The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: Fragile X mental retardation, autosomal homolog 1

Alternative Symbols: FXR1P, MYOPMIL, MYORIBF

Protein Name: Fragile X mental retardation syndrome-related protein 1

Molecular Weight: 68kDa

Gene ID: 8087

NCBI Accession: NP_005078

UniProt: P51114