FXR1 antibody (C-Term)

Catalog No. ABIN2778725

Product Details anti-FXR1 Antibody

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EQLRQIGSRS YSGRGRGRRG PNYTSGYGTN SELSNPSETE SERKDELSDW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FXR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FXR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FXR1

Target: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Alternative Name: FXR1 (FXR1 Products)

Synonyms: FXR1P antibody, wu:fb16f11 antibody, wu:fd18c10 antibody, zgc:66226 antibody, Fxr1h antibody, Fxr1p antibody, XtFxr1p antibody, fxr1h antibody, xFxr1p antibody, FXR1 antibody, 1110050J02Rik antibody, 9530073J07Rik antibody, AI851072 antibody, xfxr1 antibody, fxr1 antibody, FMR1 autosomal homolog 1 antibody, fragile X mental retardation, autosomal homolog 1 antibody, fragile X mental retardation gene 1, autosomal homolog antibody, FMR1 autosomal homolog 1 L homeolog antibody, FMR1 autosomal homolog 1 S homeolog antibody, FXR1 antibody, fxr1 antibody, Fxr1 antibody, fxr1.L antibody, fxr1.S antibody

Background: FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit.The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FXR1P
Protein Interaction Partner: UBC, TOP3B, FXR2, ORC2, CAPRIN1, FMR1, LRWD1, TDRD3, UBAP2, RANBP9, SUZ12, BMI1, CSNK2A1, CAND1, COPS5, CUL3, SIRT7, ELAVL1, SUMO2, SUMO1, HDAC5, GIGYF2, LRIF1, LUC7L2, KIAA1377, CYFIP2, PRSS23, C14orf1, CRMP1, FXR1, GBP2, CYFIP1,
Protein Size: 621

Molecular Weight: 68 kDa

Gene ID: 8087

NCBI Accession: NM_005087, NP_005078

UniProt: P51114