RBM9 antibody (N-Term)

Catalog No. ABIN2778754

The Rabbit Polyclonal anti-RBM9 antibody is suitable to detect RBM9 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for RBM9 antibody (N-Term) (ABIN2778754)

Target: RBM9 (RNA Binding Motif Protein 9 (RBM9))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBM9 Antibody

Binding Specificity: N-Term

Purpose: RBM9 Antibody - N-terminal region

Sequence: STQAHGEQSS NSPSTQNGSL TTEGGAQTDG QQSQTQSSEN SESKSTPKRL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against RBM9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110956

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBM9

Target: RBM9 (RNA Binding Motif Protein 9 (RBM9))

Alternative Name: RBM9

Background:

Background Information: RBM9 is a RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: RNA binding protein, fox-1 homolog (C. elegans) 2

Alternative Symbols: RTA, fxh, FOX2, RBM9, Fox-2, HNRBP2, HRNBP2, dJ106I20.3

Protein Name: RNA binding protein fox-1 homolog 2

Molecular Weight: 40kDa

Gene ID: 23543

NCBI Accession: NP_001026865

UniProt: O43251

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Skeletal Muscle Fiber Development