Filensin antibody (N-Term)

Catalog No. ABIN2778759

The Rabbit Polyclonal anti-Filensin antibody (ABIN2778759) specifically detects Filensin in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Saccharomyces cerevisiae and Sheep samples.

Quick Overview for Filensin antibody (N-Term) (ABIN2778759)

Target: Filensin (BFSP1) (Beaded Filament Structural Protein 1, Filensin (BFSP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig, Saccharomyces cerevisiae, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filensin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Filensin Antibody

Binding Specificity: N-Term

Purpose: BFSP1 Antibody - N-terminal region

Sequence: QVESNRQRVR DLEAERARLE RQGTEAQRAL DEFRSKYENE CECQLLLKEM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 80%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against BFSP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BFSP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095489

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Filensin

Target: Filensin (BFSP1) (Beaded Filament Structural Protein 1, Filensin (BFSP1))

Alternative Name: BFSP1

Background:

Background Information: More than 99 % of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and BFSP1 (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament.More than 99 % of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Beaded filament structural protein 1, filensin

Alternative Symbols: CP94, CP115, LIFL-H, CTRCT33

Protein Name: Filensin

Molecular Weight: 74kDa

Gene ID: 631

NCBI Accession: NP_001186

UniProt: Q12934