CDC5L antibody (Middle Region)

Catalog No. ABIN2778760

The Rabbit Polyclonal anti-CDC5L antibody (ABIN2778760) specifically detects CDC5L in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit, Horse, Dog, Guinea Pig, Goat, Cow and Saccharomyces cerevisiae samples.

Quick Overview for CDC5L antibody (Middle Region) (ABIN2778760)

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit, Horse, Dog, Guinea Pig, Goat, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC5L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDC5L Antibody

Binding Specificity: Middle Region

Purpose: CDC5L Antibody - middle region

Sequence: LHWYTGEGMD EMEFTEAESN MNDLVSEYQQ YQDATADEQG EFEEEEGEDE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CDC5L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC5L

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40347-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC5L

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Alternative Name: CDC5L

Background:

Background Information: CDC5L shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. CDC5L has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: CDC5 cell division cycle 5-like (S. pombe)

Alternative Symbols: CDC5, CEF1, PCDC5RP, CDC5-LIKE, dJ319D22.1

Protein Name: Cell division cycle 5-like protein

Molecular Weight: 92kDa

Gene ID: 988

NCBI Accession: NP_001244

UniProt: Q99459

Pathways: Activation of Innate immune Response, Chromatin Binding