APOBEC1 antibody (N-Term)
Quick Overview for APOBEC1 antibody (N-Term) (ABIN2778780)
Target
See all APOBEC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- TSEKGPSTGD PTLRRRIEPW EFDVFYDPRE LRKEACLLYE IKWGMSRKIW
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Predicted Reactivity
- Dog: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%
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Characteristics
- This is a rabbit polyclonal antibody against APOBEC1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human APOBEC1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 236 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- APOBEC1 (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1 (APOBEC1))
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Alternative Name
- APOBEC1
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Background
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APOBEC1 is a member of the cytidine deaminase enzyme family. The protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: APOBEC-1, BEDP, CDAR1, HEPR
Protein Interaction Partner: A1CF, DNAJB11, APOBEC2, BAG4, CELF2, KPNA2, APOBEC1, SYNCRIP,
Protein Size: 236 -
Molecular Weight
- 28 kDa
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Gene ID
- 339
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NCBI Accession
- NM_001644, NP_001635
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UniProt
- P41238
Target
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