SRGN antibody (N-Term)

Catalog No. ABIN2778808

Product Details anti-SRGN Antibody

Target: SRGN (serglycin (SRGN))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLKCSRLVLA LALILVLESS VQGYPTRRAR YQWVRCNPDS NSANCLEEKG

Predicted Reactivity: Human: 100%, Mouse: 91%, Rabbit: 85%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against SRGN. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 158 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRGN

Target: SRGN (serglycin (SRGN))

Alternative Name: SRGN (SRGN Products)

Background: SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.
Alias Symbols: FLJ12930, MGC9289, PPG, PRG, PRG1
Protein Interaction Partner: UBQLN1, SGTA, UBQLN4, PSRC1, CEP70, UBR4, BAG6, CCL3, PF4, GZMB, CD44, ALB,
Protein Size: 158

Molecular Weight: 15 kDa

Gene ID: 5552

NCBI Accession: NM_002727, NP_002718

UniProt: P10124

Pathways: Maintenance of Protein Location