RDBP antibody (N-Term)

Catalog No. ABIN2778821

The Rabbit Polyclonal anti-RDBP antibody is suitable to detect RDBP in samples from Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for RDBP antibody (N-Term) (ABIN2778821)

Target: RDBP (RD RNA Binding Protein (RDBP))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RDBP Antibody

Binding Specificity: N-Term

Purpose: RDBP Antibody - N-terminal region

Sequence: QSSSSTTSQG GVKRSLSEQP VMDTATATEQ AKQLVKSGAI SAIKAETKNS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RDBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RDBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40430-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RDBP

Target: RDBP (RD RNA Binding Protein (RDBP))

Alternative Name: RDBP

Background:

Background Information: RDBP is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins, however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins, however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: RD RNA binding protein

Alternative Symbols: RD, RDP, RDBP, D6S45, NELF-E

Protein Name: Negative elongation factor E

Molecular Weight: 43kDa

Gene ID: 7936

NCBI Accession: NP_002895

UniProt: P18615