SRPRA (Middle Region) antibody

Catalog No. ABIN2778844

The Rabbit Polyclonal anti-SRPRA antibody (ABIN2778844) specifically detects SRPRA in WB. The antibody is reactive with Human, Mouse, Rat, Pig, Guinea Pig, Dog and Cow samples.

Quick Overview for SRPRA (Middle Region) antibody (ABIN2778844)

Target: SRPRA

Reactivity: Human, Mouse, Rat, Pig, Guinea Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: Middle Region

Purpose: SRPRA Antibody - middle region

Sequence: EEFIQKHGRG MEKSNKSTKS DAPKEKGKKA PRVWELGGCA NKEVLDYSTP

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SRPR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRPR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40460-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: SRPRA

Background:

Targeted Subunit: alpha

Background Information: The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.

Gene Name: SRP receptor subunit alpha

Alternative Symbols: DP, SRPR, Sralpha

Protein Name: signal recognition particle receptor subunit alpha

Molecular Weight: 70kDa

Gene ID: 6734

NCBI Accession: NP_003130

UniProt: P08240